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FITC標(biāo)記的載脂蛋白C3抗體

文字:[大][中][小] 2017-5-2    瀏覽次數(shù):1117    

                                     FITC標(biāo)記的載脂蛋白C3抗體                                                                                                                                                
英文名稱Anti-APOC3/FITC
中文名稱:FITC標(biāo)記的載脂蛋白C3抗體
別    名APO C3; Apo CIII; Apo-CIII; APOC 3; ApoC III; ApoC-III; APOC3; APOC3_HUMAN; ApoCIII; Apolipoprotein C III; Apolipoprotein C-III; Apolipoprotein C3; ApolipoproteinCIII; MGC150353.  

詳細(xì)介紹:


規(guī)格:100ul 
說 明 書100ul  
研究領(lǐng)域腫瘤  心血管  細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  脂蛋白  新陳代謝  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng) Human, Cow, 
產(chǎn)品應(yīng)用ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量9kDa
性    狀Lyophilized or Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human APOC3
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

相關(guān)資料:


產(chǎn)品介紹background:
Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. It inhibits lipoprotein lipase and hepatic lipase and it is thought to delay catabolism of triglyceride-rich particles. An increase in apoC-III levels induces the development of hypertriglyceridemia

Function:
Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles. 

Subcellular Location:
Secreted. 

Tissue Specificity:
Constitutes 50% of the protein fraction of VLDL and 2% of that of HDL. Synthesized predominantly in liver and to a lesser degree in intestine.

Post-translational modifications:
O-linked glycan consists of Gal-GalNAc disaccharide, further modified with up to 3 sialic acid residues. O-glycosylated on Thr-94 with a core 1 or possibly core 8 glycan. 

DISEASE:
Hyperalphalipoproteinemia 2 (HALP2) [MIM:614028]: A condition characterized by high levels of high density lipoprotein (HDL) and increased HDL cholesterol levels. Note=The disease is caused by mutations affecting the gene represented in this entry. 

Similarity:
Belongs to the apolipoprotein C3 family.

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