利血平

英文名稱：Reserpine
CAS號：50-55-5
分析標準品,≥99.5%
分子式 C33H40N2O9 分子量608.68

基本信息:

密度1.32
溶解性 Soluble in DMSO (100 mM), chloroform (10 mg/ml), water (<1 mg/ml at 25° C), and ethanol (<1 mg/ml at 25° C).
存貯條件 儲存溫度2-8°C
描述
產品介紹 Reserpine has displayed a capacity to inhibit the transport of biogenic amines into synaptic vesicles and adrenal chromaffin granules. The mechanism behind this inhibition has been illuminated as an irreversible binding to the vesicular amine transporter. Furthermore, Reserpine has been reported to interfere with dopamine transporter activity and potently inhibit synaptosomal dopamine uptake. Reserpine is an inhibitor of VMAT 2.
別名 蛇根堿;血安平;蛇根草素;Serpalan; Serpasil; Hiserpia; Serpanray; Serpivite; Apoplon;3,4,5-Trimethoxybenzoyl methyl reserpate; (3β, 16β, 17α, 18β, 20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
生化機理 抑制兒茶酚胺(catecholamines)和5-羥色胺（serotonin）的吸收。
應用 An inhibitor of transport of biogenic amines into adrenal chromaffin granules