吳茱萸內酯

英文名稱：Evodine  
CAS號：1180-71-8
分析標準品,>98%(HPLC)  
分子式 C26H30O8 分子量470.51  

基本信息:

密度  1.39
熔點   271-272°C
存貯條件   儲存溫度2-8°C
描述  
產品介紹   檸檬苦素是一種三萜苷元(triterpenoid aglycone),來自于柑桔類水果.
別名   吳茱萸內酯 ;檸檬苦素;Limonin Limonoic acid 3,19:16,17 dilactone
生化機理  
Limonin is a triterpenoid aglycone that is a bitter principle of citrus fruits. Limonin is chemically induced carcinogenesis inhibitor and HIV-1 replication inhibitor. Limonin has anti-proliferative, proapoptotic activity on several cancer cell lines and inhibits azoxymethane-induced colon cancer in rats. Limonin also inhibits HIV-1 replication in culturedf monocytes, macrophages, and mononuclear cells, perhaps by inhibition of HIV-1 protease activity.  
應用   對幾個腫瘤細胞系具有抗增殖、抗凋亡活性，并抑制氧化偶氮甲烷（azoxymethane）誘發的大鼠結腸癌。依靠抑制HIV - 1蛋白酶活性，抑制HIV - 1病毒在單核細胞，巨噬細胞和單核細胞的復制，